Summer size linen M knitted dress OIOxrSq

Preeclampsia was once called “the disease of theories,” but research efforts this past decade have produced exciting breakthroughs that may bring us closer to causality, improve diagnosis and even prediction, and lead to prevention and/or specific treatments. Some speculation remains over different theories including: changes in biology of the placenta, the systemic inflammatory response, a variety of hormones and other proteins that are in the mother’s circulation, changes in immune factors, improper cardiovascular adaptations to the pregnant state, underlying maternal risks for cardiovascular disease, associations with insulin resistance and diabetes, and deficiencies in essential nutrients, minerals, and vitamins. 

The most plausible theories focus on the placenta and describe the disorder in two stages. In the first, the initiating cause results in the placenta producing factors (e.g., specific proteins, placental “debris”) that enter the maternal circulation and are believed responsible for producing the next stage. This is the second stage, which results in the overt maternal “disease” (high blood pressure, kidney, liver and coagulation abnormalities).  The overt disease depends not only on the action of the circulating factors from the placenta, but also the health of the mother, including diseases that may affect the vasculature (such as preexisting cardiovascular, renal, metabolic, and genetic factors; and obesity). A quick chart of potential causes can be found in our FAQstop size knitted Summer L linen sample one Only blue qCtFvwFnXP.

linen Summer size knitted dress M
A promising area of recent research involves the role of proteins produced by the placenta that inhibit angiogenesis (the production of new blood vessels).  Two of these “antiangiogenic factors” (soluble Fms-like tyrosine kinase-1, and soluble endoglin) have been shown to produce a preeclampsia like disease in rodents. Their concentrations rise in the mother’s circulation weeks to months before the disease manifests.  Placentas of women destined to develop preeclampsia overproduce these proteins that then enter the mother’s circulation.  Neutralizing their actions is now being investigated in animal models, and in some studies has reversed the disease in rodents. .  Excitement regarding these interventions is tempered by a limited understanding of the functional role of antiangiogenic substances in normal pregnancy.

If the ability of these antiangiogenic proteins to cause preeclampsia is confirmed by research in humans, why the placenta overproduces them remains unknown. Hence, many of the other areas of investigation mentioned above may be important.  Preeclampsia may have multiple causes, and other leads are being investigated, including prostaglandins, digoxin-like molecules, immunological mechanisms, autoantibodies that trigger receptors that lead to vessel constriction (agonistic autoantibodies to the angiotensin 1 receptor), oxidative stress, mitochondrial pathology, the impact of hypertension and prehypertension on endovascular health, and genes sensitive to low oxygen environments. 

Basic research into causes of preeclampsia, lacking for decades, is being revitalized, albeit more slowly than needed. While we are moving closer to historically elusive answers, the true cause of preeclampsia remains unknown. Successful ongoing  research needs far more support and funding.

M size Summer dress linen knitted
Casual knitted linen size dress M green price Special vf1Fx
Summer size linen M knitted dress OIOxrSq Summer size linen M knitted dress OIOxrSq Summer size linen M knitted dress OIOxrSq Summer size linen M knitted dress OIOxrSq
ZUZA BART OUTLET







On etsy.com you have opportunity to purchase Zuza Bart's knitwear in special prices.



Items we offer here are at least 50% discounted.







Beautiful asymmetrical linen dress, M size.



Measurements:







bust circumference: 96 cm



length back: about 90 cm















Zuza Bart is a small, family-run company with a nearly 20-year history. All new models start from a single thread and each stage is supervised by the designer, which guarantees outstanding quality. Knitting is a very difficult and time-consuming process and Zuzanna Bartecka trusts only in vintage, manual knitting machines. No other machines can cope with such a demanding yarn as linen, which is particularly difficult to process, to deliver the desired outcome. This is what makes Zuza Bart collections so unique - the complex manufacturing process that nevertheless offers great possibilities of shaping knitwear.







Zuza Bart started experimenting with linen when it was still practically unheard of to use linen for knitwear. No other yarn offers such possibilities of forming and accentuating shape. No other yarn gains refinement as it is worn, washed and exposed to sunlight. Linen adapts itself to the bodyline and can be worn in summer to keep you cool and in winter when it keeps your body warm.







On Etsy you'll find our unique models that aren't available in regular production. What we offer you here are funky, "only one" items.







This also means that we offer models as they are seen on photos- we do not have other colours, sizes or fabrics.







How it works:







1. You're finding what you love and what suits you perfectly.



2. You're wearing it proudly being sure no one else has the same piece as you have.







Our clothes are designed for women who want to be noticed, who want to be seen, who appretiate natural fabrics and quirky style.
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